The X1 open reading frame of the SARS virus encodes a potentially unique protein not found in other coronaviruses. Here we present results of bioinformatic analyses that predict the X1 protein to bind calcium. The regulation of calcium homeostasis and calcium-mediated signalling pathways in infected cells may affect cell fate and contribute to the unique pathogenesis of this virus.

Abhishek Narain Singh

School of Management & Entrepreneurship

IIT Jodhpur

D. Gupta

S. Jameel

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Journal	Current Science
ISSN	00113891