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What do we know about DNA mechanics so far?
A. Aggarwal, S. Naskar, A.K. Sahoo, , A. Garai, P.K. Maiti
Published in Elsevier Ltd
PMID: 32615513
Volume: 64
Pages: 42 - 50
The DNA molecule, apart from carrying the genetic information, plays a crucial role in a variety of biological processes and finds applications in drug design, nanotechnology and nanoelectronics. The molecule undergoes significant structural transitions under the influence of forces due to physiological and non-physiological environments. Here, we summarize the insights gained from simulations and single-molecule experiments on the structural transitions and mechanics of DNA under force, as well as its elastic properties, in various environmental conditions, and discuss appealing future directions. © 2020 Elsevier Ltd
About the journal
JournalData powered by TypesetCurrent Opinion in Structural Biology
PublisherData powered by TypesetElsevier Ltd
Open AccessNo