This communication describes the synthesis, structural investigation and tubulin binding of purine rare imino-tautomer based Ag(i) and Hg(ii)-carbene complexes. These complexes exhibit cytotoxicity through tubulin interaction by binding to a site close to the GTP binding site. © 2014 The Royal Society of Chemistry.

Surajit Ghosh

Department of Bioscience & Bioengineering

IIT Jodhpur

S. Khanna

B. Jana

A. Saha

P. Kurkute

S. Verma

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The sprawling 852-acre IIT Jodhpur campus is a majestic tribute to the deep-rooted diverse cultural heritage of the region. The campus is an architectural masterpiece, which is slated to become an international exemplar of sustainability with net-zero energy, and advanced water and waste management strategies.&rdquo;

Dalton Transactions

Targeting cytotoxicity and tubulin polymerization by metal-carbene complexes on a purine tautomer platform

Journal	Data powered by SciSpaceDalton Transactions
Publisher	Data powered by SciSpaceRoyal Society of Chemistry
ISSN	14779226