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Targeted delivery of a novel peptide-docetaxel conjugate to MCF-7 cells through neuropilin-1 receptor: Reduced toxicity and enhanced efficacy of docetaxel
A. Saha
,
S. Mohapatra
,
P. Kurkute
,
B. Jana
,
J. Sarkar
,
P. Mondal
,
Surajit Ghosh
Published in Royal Society of Chemistry
2015
DOI:
10.1039/c5ra16741h
Volume: 5
Issue: 112
Pages: 92596 - 92601
Abstract
We have designed a novel peptide-docetaxel conjugate, which delivers docetaxel specifically to cancer cell targeting neuropilin-1 (NRP-1) receptor, thus enhancing its efficacy and acts more aggressively in breast cancer cells. © 2015 The Royal Society of Chemistry.
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Journal Details
Authors (1)
About the journal
Journal
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RSC Advances
Publisher
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Royal Society of Chemistry
ISSN
20462069
Authors (1)
Surajit Ghosh
Department of Bioscience & Bioengineering
IIT Jodhpur
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