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Synthesis and Assessment of Novel Gelatin–Chitosan Lactate Cohydrogels for Controlled Delivery and Tissue Engineering Applications
G.S. Shaw, P.M. Pandey, Y. Yogalakshmi, , S.M. Al-Zahrani, A. Anis, K. Pal
Published in Taylor and Francis Inc.
Volume: 56
Issue: 13
Pages: 1457 - 1467
The current study discusses the synthesis of novel gelatin–chitosan lactate cohydrogels. Mechanical studies indicated the viscoelastic nature of the cohydrogels. The cohydrogels were predominantly elastic in nature. Inherent mechanical stability of the cohydrogels was better than the pristine gelatin hydrogel. Incorporation of chitosan lactate improved the in vitro swelling and the drug release properties of the cohydrogels. The cohydrogels showed good antimicrobial drug delivery capacity. The properties of the developed cohydrogels demonstrated that they could be used as delivery vehicles for antimicrobial drugs. Cell proliferation study suggested that the cohydrogels supported the proliferation of the human keratinocytes. © 2017 Taylor & Francis.
About the journal
JournalData powered by TypesetPolymer - Plastics Technology and Engineering
PublisherData powered by TypesetTaylor and Francis Inc.