This study reports the use of Chlamydomonas reinhardtii at the cathode in a photosynthetic microbial fuel cell (PMFC). The PMFC produced power and current density of 15.21 W m(3) and 39 A m(3), respectively. The specific growth rate of algae culture at the cathode was 0.284 day(-1). The system achieved COD removal at 73.30\% with a Coulombic efficiency of 9.068\%. The usability of algae biomass was assessed in terms of its total phenol content (157.69 mg GAE/g algae DW), antioxidant activity (IC50 = 67.07 mu g/ml), total Chlorophyll (18.95 mg/g), total Carotenoids (2.40 mg/g), and antibacterial properties against known pathogens. Overall, the study's findings suggested that C. reinhardtii supports high power output from a PMFC and is highly resourceful in terms of valueadded products.