An efficient methodology for minimizing core supply noise in Power Delivery Networks is presented. To reduce the power supply noise, an optimal decoupling network is designed by Simulated Annealing. The cumulative impedance of Power Delivery Network is reduced using lesser number of decoupling capacitors compared to placing decoupling capacitors intuitively. The supply noise is minimized according to the requirement of system specifications and the corresponding jitter reduction is reported. © 2017 IEEE.