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Matrix metalloproteinase targeted peptide vesicles for delivering anticancer drugs
D. Bhunia, K. Pradhan, G. Das, , P. Mondal, S. Ghosh
Published in Royal Society of Chemistry
2018
PMID: 30070277
Volume: 54
   
Issue: 67
Pages: 9309 - 9312
Abstract
A matrix metalloproteinase (MMP) targeted tetrapeptide vesicle has been designed and developed, which strongly binds at a MMP9 enzymatic site. Interestingly, it has a propensity to encapsulate and deliver the doxorubicin drug specifically to the cancer cell, induces superior apoptotic death, and inhibits the metastatic cancer cell migration and growth of multicellular 3D spheroids. © The Royal Society of Chemistry.
About the journal
JournalData powered by TypesetChemical Communications
PublisherData powered by TypesetRoyal Society of Chemistry
ISSN13597345