Labelled data are not only time consuming but often expensive and difficult to procure as it involves skilful inputs by humans to tag and annotate. Contrary to this unlabelled data is comparatively easier to procure but fewer methods exist to optimally use them. Semi-Supervised Learning overcomes this problem and assists to build better classifiers by using unlabelled data along with sufficient labelled data and may actually yield higher accuracy with considerably less human input effort. But if the labelled data set is inadequate in size then the Semi-Supervised techniques are also stuck. We propose a novel framework where the small labelled dataset is appropriately augmented using the intelligent learning mechanisms of artificial immune systems to train the proposed model. The model retrains with the unlabelled data to fortify the learning mechanism. We show that the generative deep framework utilizing artificial immune system principles provides a highly competitive approach for learning in the semi-supervised environment. © 2020, Springer Nature Singapore Pte Ltd.