This work figures the conceptual background of impedimetric measurements. Impedance measurement is a convenient approach for exploring the change in electrical behavior of diverse materials. An overview of in practice impedance analysis on CHI660D electrochemical work station is presented. Detection of microorganism causing foodborne diseases using IDE and other methods, toxic metal ion quantification, environment pollutant monitoring are described applications in this work. This work also reviewed the noticeable development in impedance measurement devices based on AD5933 such as bio-impedance measurement and explosive material detection. Biological signals are detected by transducing them into electrical analogy, detection of which is not a big issue. The main challenges are to convert biological signal into electrical information. Electrochemical sensors present captivating techniques to determine the content of sample under test. Electrochemical sensing platforms come up with an appealing methodology to interpret the concentration of biological sample as these sensors directly translate biological information to an electronic one. Huge amount of sensing platforms and corresponding devices has been developed. EIS is a rapid and easily computerized technique used to characterize biomolecules, inorganic materials, having a wide range of applications. The measured impedance spectra are generally fitted to an analogous electrical circuit model which constitutes an electrical documentation of the SUT by disclosing its behavior and properties. Quick, highly selective/specific and sensitive techniques to quantify biological and biochemical molecules and other target species are of great importance in biomedical and biotechnological application. Recent developments trends for handy, portable, fast and precise impedance analyzer is discussed. AD5933 evolution kit is reviewed. ©BEIESP.