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Fe3O4 incorporated AOT-alginate nanoparticles for drug delivery
C. Sudakar, , R. Regmi, R. Naik, G. Lawes, V.M. Naik, P.P. Vaishnava, U. Toti, J. Panyam
Published in
2008
Volume: 44
   
Issue: 11 PART 2
Pages: 2800 - 2803
Abstract
Composite nanoparticles of aerosol OT-alginate hydrogel loaded with Fe 3 O4 and rhodamine 6G (R6G) in average diameter between 25 nm and 50 nm were synthesized by emulsification-cross-linking process and characterized by transmission electron microscopy (TEM) and SQUID magnetometery measurements. TEM measurements show that the Fe3 O4 particles are uniformly distributed within AOT-alginate nanoparticles. The Ca 2+ cross-linked AOT-alginate nanoparticles loaded with Fe 3O4 and rhodamine showed superparamagnetic behavior at room temperature with saturation magnetization of ∼50 emu/g of Fe 3O4. Similar behavior was exhibited by Fe 2+ crosslinked AOT-alginate nanoparticles loaded with Fe3O4 and rhodamine except it showed twice the magnetization of Ca 2+ crosslinked counterpart. A decrease in the amount of rhodamine loading for the composite nanoparticle systems as compared to the bare AOT-alginate nanoparticles was found. © 2008 IEEE.
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About the journal
JournalIEEE Transactions on Magnetics
ISSN00189464