One of the major challenges in the fabrication of glass-metal Joint is the wettability of glass sealant over the metal surface. The aim of the work was to study the wetting and spreading behavior of borosilicate glass sealant over austenitic stainless steel SS 304 and copper substrates with different surface roughness and oxidation conditions. During the wettability study of borosilicate glass sealant over the metal specimen, glass pallets were melted over the different oxidized metal specimens. The wetting behavior of borosilicate glass over metal specimen was measured in terms of contact angle and spreading area. The types of oxide and change in microstructure after oxidation were examined with the help of XRD analysis and optical microscopy. Tensile strength and hardness of the metal substrates after oxidation was also evaluated. © 2017 Trans Tech Publications, Switzerland.