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Current direction-dependent modulation of human hand motor function by intermittent theta burst stimulation (iTBS)
Y. Shirota, , W. Paulus, M. Sommer
Published in Elsevier Ireland Ltd
PMID: 28435045
Volume: 650
Pages: 109 - 113
Background Transcranial magnetic stimulation (TMS) with different current directions can activate different sets of neurons. Current direction can also affect the results of repetitive TMS. Objective: To test the influence of uni-directional intermittent theta burst stimulation (iTBS) using different current directions, namely posteroanterior (PA) and anteroposterior (AP), on motor behaviour. Methods In a cross-over design, PA- and AP-iTBS was applied over the left primary motor cortex in 19 healthy, right-handed volunteers. Performance of a finger-tapping task was recorded before and 0, 10, 20, and 30 min after the iTBS. The task was conducted with the right and left hands separately at each time point. As a control, AP-iTBS with reduced intensity was applied to 14 participants in a separate session (APweak condition). Results The finger-tapping count with the left hand was decreased after PA-iTBS. Neither AP- nor APweak-iTBS altered the performance. Conclusions Current direction had a significant impact on the after-effects of iTBS. © 2017 Elsevier B.V.
About the journal
JournalData powered by TypesetNeuroscience Letters
PublisherData powered by TypesetElsevier Ireland Ltd