We study the consequences of CPT and lepton number violation in the neutrino sector. For CPT violation we take gravity with which neutrino and antineutrino couple differently. Gravity mixes neutrino and antineutrino in an unequal ratio to give two mass eigenstates. Lepton number violation interaction together with CPT violation gives rise to neutrino-antineutrino oscillation. Subsequently, we study the neutrino flavor mixing and oscillation under the influence of gravity. It is found that gravity changes flavor oscillation significantly which influences the relative abundance of different flavors in present universe. We show that the neutrinoless double beta decay rate is modified due to the presence of gravity-the origin of CPT violation, as the mass of the flavor state is modified. © 2008 The American Physical Society.