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Biology-Oriented Synthesis of 3,3-Spiro(2-tetrahydrofuranyl)oxindoles
, C. Golz, C. Strohmann, A.P. Antonchick, H. Waldmann
Published in Georg Thieme Verlag
Volume: 49
Issue: 1
Pages: 87 - 95
A biology-oriented synthesis of 3,3-spiro(2-tetrahydrofuranyl)oxindole derivatives is realized through the rhodium(II)-catalyzed three-component reaction of diazoamides, aldehydes and β-nitrostyrenes. The reactions are conducted under mild conditions and the products are obtained in moderate to good yields with excellent regio- and diastereoselectivity. © 2017 Georg Thieme Verlag Stuttgart, New York.
About the journal
JournalSynthesis (Germany)
PublisherGeorg Thieme Verlag