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An in-Depth Analysis of the Swelling, Mechanical, Electrical, and Drug Release Properties of Agar–Gelatin Co-Hydrogels
P.M. Pandey, S.K. Nayak, G.S. Shaw, K. Uvanesh, , S.M. Al-Zahrani, A. Anis, K. Pal
Published in Taylor and Francis Inc.
2017
Volume: 56
   
Issue: 6
Pages: 667 - 677
Abstract
Agar–gelatin-based co-hydrogels were prepared with different compositions of the agar and the gelatin fractions. The intermolecular hydrogen bonding was higher in the co-hydrogels as compared to the gelatin hydrogel. Swelling studies indicated diffusion-mediated swelling. The electrical stability of the co-hydrogels was higher as compared to the gelatin hydrogel. Though the firmness of the co-hydrogels was higher, Weichert model of viscoelasticity indicated that the inherent mechanical stability of the gelatin hydrogel was superior. The release of ciprofloxacin hydrochloride was predominately Fickian diffusion-mediated. In gist, the co-hydrogels can be tried as polymeric constructs for controlled drug delivery applications. © 2017 Taylor & Francis.
About the journal
JournalPolymer - Plastics Technology and Engineering
PublisherTaylor and Francis Inc.
ISSN03602559