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A diversity-oriented synthesis of polyheterocycles: Via the cyclocondensation of azomethine imine
A.J. Ansari, R.S. Pathare, A. Kumawat, A.K. Maurya, S. Verma, V.K. Agnihotri, R. Joshi, , A. Sharon, R.T. PardasaniShow More
Published in Royal Society of Chemistry
Volume: 43
Issue: 35
Pages: 13721 - 13724
Pd-Catalyzed sequential reactions to afford skeletally diverse molecules are described. The reaction involved azomethine imine formation and a cyclocondensation reaction as individual steps. The methodology provides excellent regio- and stereocontrol. Skeletal diversity was ensured by changing the electrophilic counterpart of azomethine imine. Due to its broader diversity and complexity, the DOS methodology is likely to benefit drug discovery and development in the future. This journal is © 2019 The Royal Society of Chemistry and the Centre National de la Recherche Scientifique.
About the journal
JournalData powered by TypesetNew Journal of Chemistry
PublisherData powered by TypesetRoyal Society of Chemistry
Open AccessNo